Figure 1 | Scientific Reports

Figure 1

From: Autologous skeletal muscle derived cells expressing a novel functional dystrophin provide a potential therapy for Duchenne Muscular Dystrophy

Figure 1

Schematic illustration of mini-dystrophin constructs and the titration of lentivirus using different methods.

(A) Schematic illustration of mini-dystrophin constructs compared to the full-length dystrophin. The sizes of mini-dystrophin constructs are given on the right. Individual deletions are outlined in grey and domains highlighted in different colors as indicated. (B) Titration of lentivirus using different methods, showing that the titration of the lentiviruses was limited by the size (bp) of the inserted transgene. NIGW: pRRL.SFFV.neo-IRES-GFP; SC2: SFFV-C2-GFP; DC2: hDesmin-C2-GFP; SC1: SFFV-C1-GFP; DC1: hDesmin-C1-GFP.

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