Table 2 Univariate and multivariate analysis for overall survival*.
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age (y) | 1.003 | 0.986–1.020 | 0.720 | – | – | – |
Sex | ||||||
Female vs. male | 0.920 | 0.541–1.564 | 0.758 | – | – | – |
Etiology | ||||||
Hepatitis infection vs. Other | 0.749 | 0.398–1.410 | 0.370 | – | – | – |
Child-Pugh class | ||||||
B vs. A | 0.943 | 0.490–1.814 | 0.861 | – | – | – |
ECOG | ||||||
2 vs. 0–1 | 2.208 | 1.294–3.180 | 0.002 | 1.952 | 1.239–3.076 | 0.004 |
PVTT | ||||||
Yes vs. No | 1.658 | 1.124–2.447 | 0.011 | 1.398 | 0.934–2.093 | 0.103 |
Extrahepatic spread | ||||||
Yes vs. No | 1.376 | 0.938–2.017 | 0.103 | 1.214 | 0.825–1.787 | 0.324 |
No. of HCC nodules | ||||||
≥2 + Diffused vs. 1 | 1.072 | 0.735–1.565 | 0.718 | |||
Baseline AFP (ng/ml) | ||||||
≥200 vs 200 | 1 | 0.669–1.494 | 0.999 | – | – | – |
AFP change | ||||||
Nonresponse vs. response | 1.863 | 1.268–2.738 | 0.002 | 1.710 | 1.147–2.551 | 0.009 |
