Table 3 Haplotype identification and association analyses in the discovery sample.

From: Associations of Plasma FGF2 Levels and Polymorphisms in the FGF2 Gene with Obesity Phenotypes in Han Chinese Population

Block

SNPsa

Haplotypeb

Frequency

BMI

Fat Mass

WHRadjBMI

β

P

β

P

β

P

Block 1

1–3

CCA

0.155

0.144

0.328

0.132

0.592

1.03 × 10−3

0.723

CCG

0.162

0.132

0.374

0.273

0.270

1.62 × 10−3

0.579

TTG

0.162

−0.268

0.053

−0.904

8.71 × 10 − 5

−4.36 × 10−3

0.109

CTG

0.517

0.018

0.871

0.348

0.055

1.20 × 10−3

0.574

Block 2

4,5

TA

0.120

−0.374

0.017

−0.999

1.39 × 10 − 4

−4.23 × 10−3

0.172

TT

0.185

0.048

0.745

−0.127

0.605

1.73 × 10−3

0.548

CT

0.695

0.202

0.107

0.724

5.20 × 10 − 4

1.41 × 10−3

0.566

Block 3

6,8–11

ACCTC

0.440

0.167

0.103

0.440

9.82 × 10−3

−1.71 × 10−4

0.932

GTTCA

0.495

−0.121

0.237

−0.376

0.027

2.09 × 10−3

0.299

  1. Significant P values after multiple testing adjustment (P < 0.0056) are shown in bold.
  2. aThe IDs of SNPs correspond to those in Table 2.
  3. bHaplotypes with estimated frequencies more than 0.05 are listed.
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