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Figure 1

From: Dysregulated expression of IDO may cause unexplained recurrent spontaneous abortion through suppression of trophoblast cell proliferation and migration

Figure 1

IDO expression and activity are decreased in villi from URSA patients compared to those from normal pregnant women (CTL).

(A) Representative images of IDO expression in villous tissue. Immunostaining verifies IDO expression in tissue sections. A Brownish color represents positive staining. Magnification: 200×. (B) HPLC analysis of IDO activity, expressed as the ratio of Kyn to Trp. (C) Western blot analysis of IDO protein using GAPDH as an internal control. (D) Statistical analysis of western blot results in C (n = 20; Student’s t-test; *p < 0.05, ***p < 0.001).

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