Figure 3 | Scientific Reports

Figure 3

From: Dysregulated expression of IDO may cause unexplained recurrent spontaneous abortion through suppression of trophoblast cell proliferation and migration

Figure 3

Inhibition of IDO with l-1mT or IDO-specific shRNA suppressed the migration of HTR-8/SVneo cells.

(A) Representative images from Transwell migration assay. Cells were treated with vehicle or l-1mT (top) or with control or IDO-specific shRNA (bottom). (B) Statistical analysis of the effect of l-1mT on HTR-8/SVneo cell migration (n = 3; Student’s t-test; **p < 0.01). (C) Statistical analysis of the effect of IDO knockdown on HTR-8/SVneo cell migration (n = 3; Student’s t-test; **p < 0.01, ***p < 0.001).

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