Figure 5 | Scientific Reports

Figure 5

From: Self-Styled ZnO Nanostructures Promotes the Cancer Cell Damage and Supresses the Epithelial Phenotype of Glioblastoma

Figure 5

Nanostructures accumulate ROS inside cells is essential factor for cell death.

(A) Effects of ZnO-NSts (NPls, NSs, NRs, NFs) on the reactive oxygen species (ROS) level in T98G cell lines. ROS values (in MFI, mean florescence intensity) presented are mean ± SD (n = 3). (B) Representative images of ZnO-NRs treated T98G cells after staining with DCFHDA dye. Each figure has scale bar of 50 μm. (C) ROS level in T98G cells after ZnO-NRs treated T98G cells in the presence of NAC (10 μM, N-acetyl L-cysteine, well known ROS inhibitor). Error bars represent the ± SD (n = 3). Student’s t-test was performed, *p < 0.05, δp < 0.01 and #p < 0.001.

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