Table 1 Baseline demographics and clinical information of study subjects and their comparators.
From: Effects of acute critical illnesses on the performance of interferon-gamma release assay
ICU patients (n = 118) | Diabetic patients (n = 152) | |
---|---|---|
Age, years | 62 ± 13 | 59 ± 11 |
Male sex | 69 (59) | 90 (59) |
Body mass index, kg/m2 | 23 ± 5 | 25 ± 4 |
APACHE II score | 21 ± 9 | NA |
Mycobacterium tuberculosis status | ||
BCG vaccination | 105 (89) | 132 (87) |
History of active tuberculosis | 7 (6) | 4 (3) |
Active tuberculosis | 3 (3) | 1 (1) |
Admitting diagnoses | ||
Respiratory | 57 (48) | NA |
Gastrointestinal | 16 (14) | NA |
Cardiovascular | 11 (9) | NA |
Neurologic | 11 (9) | NA |
Genitourinary | 3 (3) | NA |
Other sepsis | 12 (10) | NA |
Others | 8 (7) | NA |
Comorbidities | ||
Hypertension | 57 (48) | 71 (47) |
Malignancy | 48 (41) | 2 (1) |
Diabetes mellitus | 44 (37) | 152 (100) |
Cerebrovascular accident | 23 (20) | 7 (5) |
Liver cirrhosis | 16 (14) | 2 (1) |
Heart failure | 15 (13) | 2 (1) |
End-stage renal disease | 11 (9) | 3 (2) |
Organ transplantation | 6 (5) | 1 (1) |
Autoimmune disease | 6 (5) | 4 (3) |
Lab testing | ||
Haemoglobin, g/dl | 10.5 ± 2.6 | NA |
White blood cells, k/mcl | 12.6 ± 0.8 | NA |
Lymphocytes, k/mcl | 1.2 ± 1.1 | NA |
Albumin, g/dl | 2.8 ± 0.6 | NA |
QFT-GIT results | ||
Positive | 10 (9) | 35 (23) |
Negative | 36 (31) | 112 (74) |
Indeterminate | 72 (61) | 5 (3) |
Outcomes | ||
ICU mortality | 28 (24) | NA |
Hospital mortality | 43 (36) | NA |