Table 4 Comparison between patients with concordant and persistent indeterminate interferon-γ release assay results (n = 66).
From: Effects of acute critical illnesses on the performance of interferon-gamma release assay
Paired QFT-GIT results | P value | ||
|---|---|---|---|
Positive-positive or negative-negative | Indeterminate-indeterminate | ||
(n = 31) | (n = 35) | ||
Age, years | 62 ± 13 | 62 ± 14 | 0.957 |
Male sex | 15 (48) | 20 (57) | 0.477 |
Body mass index, kg/m2 | 24 ± 5 | 23 ± 4 | 0.333 |
APACHE II score | |||
<15 | 15 (48) | 6 (17) | 0.001 |
15–25 | 14 (45) | 14 (40) | |
>25 | 2 (7) | 15 (43) | |
Active or history of TB | 2 (7) | 2 (6) | 1.000 |
Admitting diagnoses | |||
Respiratory | 11 (36) | 17 (49) | 0.283 |
Gastrointestinal | 3 (10) | 6 (17) | |
Cardiovascular | 7 (23) | 2 (6) | |
Neurologic | 5 (16) | 4 (11) | |
Others | 5 (16) | 6 (17) | |
Comorbidities | |||
Hypertension | 17 (55) | 19 (54) | 0.964 |
Malignancy | 12 (39) | 13 (37) | 0.896 |
Diabetes mellitus | 8 (26) | 15 (43) | 0.147 |
Cerebrovascular accident | 6 (19) | 9 (26) | 0.538 |
Liver cirrhosis | 5 (16) | 5 (14) | 1.000 |
Heart failure | 5 (16) | 5 (14) | 1.000 |
End-stage renal disease | 2 (7) | 3 (9) | 1.000 |
ICU events | |||
Blood transfusion | 15 (48) | 23 (66) | 0.155 |
Use of vasopressors | 10 (32) | 18 (51) | 0.116 |
Renal replacement therapy | 5 (16) | 9 (26) | 0.342 |
Lab testing | |||
Haemoglobin, g/dl | 11.2 ± 3.0 | 10.2 ± 2.4 | 0.154 |
White blood cells, k/mcl | 11.2 ± 8.1 | 13.1 ± 6.9 | 0.309 |
Lymphocytes, k/mcl | 1.3 ± 1.0 | 1.0 ± 1.0 | 0.247 |
Albumin, g/dl | |||
<2.6 | 6 (19) | 19 (54) | 0.009 |
2.6–3 | 10 (32) | 9 (26) | |
>3 | 15 (48) | 7 (20) | |
Hospital mortality | 1 (3) | 9 (26) | 0.015 |
