Table 5 Factors associated with indeterminate interferon-γ release assay results.
From: Effects of acute critical illnesses on the performance of interferon-gamma release assay
QFT-GIT results | P value | ||
|---|---|---|---|
Positive/Negative (n = 46) | Indeterminate (n = 72) | ||
Age, years | 62 ± 14 | 62 ± 13 | 0.938 |
Male sex | 25 (54) | 44 (61) | 0.467 |
Body mass index, kg/m2 | 24 ± 5 | 23 ± 4 | 0.540 |
APACHE II score | 17 ± 8 | 24 ± 9 | <0.001 |
Active TB or history of active TB | 4 (9) | 6 (8) | 1.000 |
Admitting diagnoses | |||
Respiratory | 22 (48) | 35 (49) | 0.390 |
Gastrointestinal | 5 (11) | 11 (15) | |
Cardiovascular | 7 (15) | 4 (6) | |
Neurologic | 5 (11) | 6 (8) | |
Others | 7 (15) | 16 (22) | |
Comorbidities | |||
Hypertension | 23 (50) | 34 (47) | 0.768 |
Malignancy | 20 (44) | 28 (39) | 0.621 |
Diabetes mellitus | 17 (37) | 27 (38) | 0.953 |
Cerebrovascular accident | 9 (20) | 14 (19) | 0.987 |
Liver cirrhosis | 6 (13) | 10 (14) | 0.896 |
Heart failure | 6 (13) | 9 (13) | 0.931 |
End-stage renal disease | 3 (7) | 8 (11) | 0.525 |
Lab testing | |||
Haemoglobin, g/dl | 10.9 ± 2.9 | 10.3 ± 2.4 | 0.212 |
White blood cells, k/mcl | 12.4 ± 0.8 | 12.7 ± 0.8 | 0.869 |
Lymphocytes, k/mcl | 1.3 ± 0.9 | 1.1 ± 1.2 | 0.351 |
Albumin, g/dl | 3.0 ± 0.6 | 2.7 ± 0.5 | 0.002 |
