Figure 1 | Scientific Reports

Figure 1

From: A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population

Figure 1

Effect of the AKT1 rs2494752 polymorphism on the AKT1 promoter activity.

(A) Schematic representation of reporter plasmids containing the AKT1 rs2494752 A or G allele, which was inserted at upstream of the luciferase reporter gene in the pGL3-Basic plasmid. (B) The two constructs were transiently transfected into the Hela, SGC-7901, HGC-27 and AGS cells, respectively. All of the constructs were cotransfected with pRL-SV40 to standardize the transfection efficiency. Values were means ± SD from more than 3 separate experiments that were each performed in triplicate.

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