Table 2 Multivariate linear regression of HbA1c level.

From: Glycated Hemoglobin and Outcomes in Patients with Advanced Diabetic Chronic Kidney Disease

Variables

All

CKD stage 3-4

CKD stage 5

β(95% CI)

p -value

β(95% CI)

p -value

β(95% CI)

p -value

Age (years)

−0.009 (−0.014 to −0.003)

0.002

−0.009 (−0.016 to −0.002)

0.010

−0.012 (−0.021 to −0.003)

0.010

Male vs.female

0.029 (−0.116 to 0.174)

0.693

−0.060 (−0.254 to 0.134)

0.546

0.116 (−0.097 to 0.329)

0.283

CVD

0.030 (−0.113 to 0.173)

0.680

0.015 (−0.174 to 0.205)

0.876

0.061 (−0.150 to 0.272)

0.573

BMI (m2/kg)

0.002 (−0.015 to 0.002)

0.795

0.005 (−0.018 to 0.028)

0.684

−0.005 (−0.031 to 0.022)

0.738

MAP (mmHg)

−0.002 (−0.007 to 0.003)

0.421

0.004 (−0.003 to 0.010)

0.285

−0.009 (−0.017 to−0.002)

0.011

eGFR (ml/min/1.73 m2)

0.012 (0.005 to 0.018)

<0.001

0.003 (−0.005 to 0.012)

0.451

0.070 (0.031 to 0.108)

<0.001

Log (UPCR)

0.308 (0.146 to 0.469)

<0.001

0.254 (0.060 to 0.448)

0.010

0.233 (−0.075 to 0.541)

0.138

Albumin (g/dl)

−0.210 (−0.343 to −0.077)

0.002

−0.206 (−0.382 to −0.029)

0.022

−0.199 (−0.397 to −0.001)

0.049

Hemoglobin (g/dl)

0.099 (0.058 to 0.141)

<0.001

0.072 (0.021 to 0.123)

0.006

0.152 (0.076 to 0.228)

<0.001

Log (cholesterol)

2.098 (1.524 to 2.672)

<0.001

2.142 (1.391 to 2.892)

<0.001

1.747 (0.871 to 2.623)

<0.001

Log (CRP)

0.059 (−0.011 to 0.130)

0.097

0.079 (−0.011 to 0.168)

0.085

0.024 (−0.088 to 0.135)

0.677

Phosphate (mg/dl)

−0.063 (−0.133 to 0.006)

0.072

0.017 (−0.092 to 0.127)

0.757

−0.010 (−0.103 to 0.082)

0.832

  1. Abbreviations: HbA1c, glycated hemoglobin; CKD, chronic kidney disease; CVD, cardiovascular disease; BMI, body mass index; MAP, mean arterial pressure; eGFR, estimated glomerular filtration rate; UPCR, urine protein-to-creatinine ratio; CRP, C-reactive protein.
  2. P < 0.05 indicated a significantly associated with HbA1c levels.