Table 4 Cytotoxic Evaluation of Compounds 1–5, 7–11 and 13–14a.
From: Cytotoxic Rocaglate Derivatives from Leaves of Aglaia perviridis
Compound | HepG2 b | HL-60 c | MCF-7 e | HT-29 d |
---|---|---|---|---|
1 | 0.014 | 0.009 | 0.009 | 0.008 |
2 | >50.00 | >50.00 | >50.00 | >50.00 |
3 | >50.00 | >50.00 | >50.00 | >50.00 |
4 | >50.00 | >50.00 | >50.00 | >50.00 |
5 | 10.9 | 2.2 | 8.5 | 1.4 |
7 | >50.00 | >50.00 | >50.00 | >50.00 |
8 | >50.00 | >50.00 | >50.00 | >50.00 |
9 | 27.7 | 29.4 | 36.0 | 23.1 |
10 | 0.016 | 0.013 | 0.008 | 0.008 |
11 | 0.006 | 0.007 | 0.008 | 0.008 |
13 | 23.0 | 19.5 | 31.1 | 16.3 |
14 | >50.00 | >50.00 | >50.00 | >50.00 |
Taxolf | 0.002 | |||
cis-platinumg | 8.2 | 2.5 | 6.4 |