Figure 7 | Scientific Reports

Figure 7

From: Comparative three-dimensional connectome map of motor cortical projections in the mouse brain

Figure 7

Summary of topography patterns.

(A) The upper panel represents a conventional wiring diagram of connections from motor cortical areas to thalamic nuclei based on a previous study, summarized as a simple algorithmic convergent model34. The bottom panel is a proposed connectivity diagram considering projection-based parcellation patterns based on the present results. The tips of arrows indicate the relative spatial positions. The thickness of arrows in both panels indicates the degree of projection; quantitative data are shown in Oh et al. (2014) and Table 1. Connections from the motor cortex to other brain regions are omitted for simplicity. (B) 3D illustrations summarizing topographic segregation patterns of cortical outputs to target nuclei, showing spatial relationships along the anterior-posterior (AP), dorsal-ventral (DV) and medial-lateral (ML) axis and the core-capsular (CC) pattern. Thalamic nuclei belong to each category were indicated next to the 3D schema. Color-coding is the same as the bottom panels of (A). Abbreviations of all brain regions are presented in Table 1.

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