Table 1 Anthropometric, clinical and biochemical parameters and adipsin levels of normal pregnant women

From: Serum Adipsin Levels throughout Normal Pregnancy and Preeclampsia

Variable

Normal pregnancy (n = 54)

P-value in the Friedman’s test*

P-value in the post-hoc analyses

EP

MP

LP

EP Vs MP

EP Vs LP

MP Vs LP

Weight, Kg (mean ± SD)

55.6 (+/− 6.9)

60.2 (+/− 7.6)

64.3 (+/− 7.4)

0.00***

0.00***

0.00***

0.00***

BMI, Kg/m2 (median (IQR))

22.34 (20.46–23.7)

23.96 (22.52–25.89)

25.95 (24.4–27.48)

0.00***

0.00***

0.00***

0.00***

Gestational age, weeks (median (IQR))

12.1 (11.5–12.5)

24.3 (24.13–24.6)

34.4 (34.2–35.2)

0.00***

0.00***

0.00***

0.00***

Systolic BP, mmHg (median (IQR))

95 (90–100)

90 (86–100)

97 (90–102)

0.03*

0.12

0.38

0.04*

Diastolic BP, mmHg (median (IQR))

60 (60–63.5)

60 (58–60)

62 (60–69.5)

0.00**

0.22

0.07

0.01**

Mean BP, mmHg (mean ± SD)

72.3 (+/− 5.5)

71 (+/− 5.2)

74.2 (+/− 7.1)

0.01*

0.13

0.03*

0.01**

Glucose, mg/dL (median (IQR))

78 (73–82.75)

72 (69–77.75)

73.5 (69–77.75)

0.00***

0.00***

0.00**

0.72

Insulin, ng/mL (median (IQR))

9.5 (5.75–12)

11.2 (8.3–14.5)

12.3 (8.05–17.52)

0.00**

0.02*

0.00***

0.03*

HOMA-IR (median (IQR))

1.695 (1.129–2.217)

1.9 (1.452–2.631)

2.255 (1.575–3.139)

0.02*

0.14

0.00***

0.01*

Total cholesterol, mg/dL (mean ± SD)

166.3 (+/− 31.3)

218.7 (+/− 37.5)

247.9 (+/− 48.4)

0.00***

0.00***

0.00***

0.00***

HDL-cholesterol, mg/dL (mean ± SD)

57.4 (+/− 10.8)

69.3 (+/− 11.5)

67.2 (+/− 11.4)

0.00***

0.00***

0.00***

0.13

LDL-cholesterol, mg/dL (mean ± SD)

119.3 (+/− 33.3)

146.7 (+/− 43.2)

157 (+/− 41.5)

0.00***

0.00***

0.00***

0.01**

VLDL-cholesterol, mg/dL (median (IQR))

21.58 (17.54–25.98)

35.46 (28.06–43.24)

46.54 (40.37–56.14)

0.00***

0.00***

0.00***

0.00***

Triglycerides, mg/dL (median (IQR))

107.9 (87.7–129.9)

177.3 (140.3–216.2)

223.6 (201.1–282.4)

0.00***

0.00***

0.00***

0.00***

Adipsin, ng/mL (mean ± SD)

4381 (+/− 663.4)

4083 (+/− 655.1)

4314.5 (+/− 665)

0.04*

0.01**

0.68

0.02*

Leptin, pg/mL (mean ± SD)

23461.12 (+/− 9011.357)

34112.42 (+/− 20165.563)

48144.76 (+/− 31264.723)

0.00***

0.00***

0.00***

0.00***

  1. Non-normally distributed data are listed as median (IQR). Normally distributed data are listed as mean ± SD. EP = early pregnancy, MP = middle pregnancy, LP = late pregnancy, PP = three months postpartum. HOMA (Homeostasis Model Assessment). *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001.
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