Figure 6: Peripheral exosomes modulate the expression of GATA3 and Foxp3 in Th2 cells. | Scientific Reports

Figure 6: Peripheral exosomes modulate the expression of GATA3 and Foxp3 in Th2 cells.

From: Donor-derived exosomes induce specific regulatory T cells to suppress immune inflammation in the allograft heart

Figure 6

CD4+ T cells were isolated from the naive mouse hearts and the allograft hearts (A,B); OVA-specific polarized Th2 cells were prepared (C,D). The cells were treated as denoted below the bars. The Western blots show the protein levels of GATA3 and Foxp3. The bars below the blots indicate the integrated density of the blots. EE: Exosome extracts (5 μg/ml). Ab: Anti-MMP1a antibody (1 μg/ml). PAR2-n: PAR2-deficient mice. The data are representative of 3 independent experiments.

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