Figure 1 | Scientific Reports

Figure 1

From: Skeletal muscle alkaline Pi pool is decreased in overweight-to-obese sedentary subjects and relates to mitochondrial capacity and phosphodiester content

Figure 1

(a) An in vivo localizer image of the human thigh with the depicted coil position. (b) Highly spectrally resolved representative 31P-MR spectra from an obese sedentary and lean active subject, scaled to PCr signal intensity. The area of Pi and PDE peaks is enlarged. Note higher Pi2 and lower PDE signal intensity in the L/Ac subject. (c) Saturation transfer spectra showing the effect of γ-ATP saturation (solid line) on its chemical exchange partner, Pi, compared with the control experiment (dashed line). (d) Time course of the 31P spectra during a dynamic 31P-MRS experiment. Note the PCr signal depletion during exercise and its re-synthesis during recovery.

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