Table 6 Association between ABCB1 rs1045642 and hypertension of patients treated with sorafenib.

From: The influence of genetic variants of sorafenib on clinical outcomes and toxic effects in patients with advanced renal cell carcinoma

 

Normal, n (%)

Severe, n (%)

Adjusted P *

OR (95% CI) *

CC

36 (40.4)

3 (15.0)

1.00 (reference)

CT

41 (47.1)

12 (60.0)

0.067

3.51 (0.92–13.44)

TT

10 (11.5)

5 (25.0)

0.028

6.00 (1.22–29.53)

CT + TT

51 (58.6)

17 (85.0)

0.037

4.00 (1.09–14.67)

  1. *Derived from logistic regression model.