Figure 8 | Scientific Reports

Figure 8

From: Rapamycin attenuates acute lung injury induced by LPS through inhibition of Th17 cell proliferation in mice

Figure 8

Rapamycin did not promote Treg cells proliferation in vivo and vitro.

(A) The expression of FOXP3 mRNA in the lungs. (B) The protein level of FOXP3 in the lungs. (C) The level of IL-10 in the BALF and spleen homogenate. (D) The expression of FOXP3 mRNA in mixed lymphocytes reaction. (E) The expression of FOXP3 protein in mixed lymphocytes reaction. C: control; L: LPS; R: rapamycin. The mice (A–C) were harvested on D2. The different superscript letters (a–c) represent a significant difference in these columns (P < 0.05). All mice were wild type, with 3~5 mice per group.

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