Table 1 Baseline characteristics and clinical features of anaphylaxis patients according to the development of hypotension.

From: Should adrenaline be used in patients with hemodynamically stable anaphylaxis? Incident case control study nested within a retrospective cohort study

Variables

no hypotension (n = 300)

hypotension (n = 40)

P Value

Demographic factor

 Age, years

46.0 ± 15.5

42.7 ± 13.9

0.208

 Male sex

145 (48.3)

18 (45.0)

0.738

Comorbidity

 Hypertension

39 (13.0)

5 (12.5)

1.000

 Diabetes mellitus

11 (3.7)

0 (0.0)

0.374

 Cardiac disease

14 (4.7)

3 (7.5)

0.705

 Neoplasm

29 (9.7)

5 (12.5)

0.781

 CKD

2 (0.7)

1 (2.5)

0.314

 Bronchial asthma

13 (4.3)

1 (2.5)

1.000

 History of allergy

109 (36.3)

13 (32.5)

0.727

 History of anaphylaxis

25 (8.3)

3 (7.5)

1.000

Symptoms and Signs

 Mucocutaneous

261 (87.0)

34 (85.0)

0.803

 Cardiovascular

110 (36.7)

17 (42.5)

0.490

 Pulmonary

203 (67.7)

24 (60.0)

0.373

 Gastrointestinal

93 (31.0)

19 (47.5)

0.048

 Neurologic

63 (21.0)

21 (52.5)

0.000

Trigger

 Drug

75 (25.0)

20 (50.0)

0.001

 Contrast media

48 (16.0)

3 (7.5)

0.236

 Food

106 (35.3)

10 (25.0)

0.218

 Insect venom

18 (6.0)

2 (5.0)

1.000

 Contact

4 (1.3)

1 (2.5)

0.467

 Idiopathic

47 (15.7)

4 (10.0)

0.480

 Severe on severity Gradea

48 (16.0)

9 (22.5)

0.365

Initial vital signs

 Systolic BP, mmHg

129.3 ± 23.4

114.1 ± 24.7

0.000

 Diastolic BP, mmHg

81.1 ± 17.3

70.3 ± 27.7

0.020

 Heart rate, beats/min

90.9 ± 21.4

88.8 ± 23.2

0.562

 Respiratory rate, breaths/min

21.6 ± 3.6

22.9 ± 5.7

0.170

 Oxygen saturation, %

97.5 ± 2.6

96.3 ± 3.6

0.052

  1. CKD: chronic kidney disease; BP: blood presssure.
  2. Values are expressed as mean ± SD, n (%).
  3. aSevere was defined as cyanosis or SpO2 ≤ 92%, hypotension (systolic BP < 90 mm Hg), confusion, collapse, loss of consciousness, or incontinence at admission.