Figure 7 | Scientific Reports

Figure 7

From: Corticotropin releasing factor excites neurons of posterior hypothalamic nucleus to produce tachycardia in rats

Figure 7

Responses of RVLM, RVMM and DMNV neurons to microinjection of CRF into the PH in rats.

(A1,A2) The upper and middle peristimulus time histograms of A1 show two single RVLM neurons increased or decreased firing rate in response to microinjection of CRF into the PH, respectively. The lower histogram in A1 shows a non-responsive RVLM neuron to the microinjection. The group data with statistical results obtained from 80 recorded RVLM neurons is shown in A2. Note that 46.3% (37/80) RVLM neurons were excited. (B1,B2) RVMM neurons also showed increase, decrease, or no change in firing rate in response to microinjection of CRF into the PH, respectively. The layout of this panel is the same with (A1,A2). (C1,C2) Firing rate of DMNV neurons exhibited no change in response to microinjection of CRF into the PH. Statistical significance was determined using Student’s t test. n.s. no significance, *P < 0.05, **P < 0.01.

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