Figure 2

Region of interest analysis for psychophysiological interaction for Painā>āNo Pain.
Percent change in connectivity seeded in ACC (a) or raINS (b) for ROIS. After controlling for ICU-Unemotional and ICU-Uncaring scores, as well as CD symptoms, age, gender, race-ethnicity and maternal education, ICU-Callous scores predicted deceased functional connectivity seeded in anterior cingulate (c), with right anterior insula (d) and left amygdala (e). Plots show partial correlations, with the respective ROI marked in red. Error bars represent SEM. *FDR-corrected pā<ā0.05, **FDR-corrected pā<ā0.01.