Figure 1
From: Predicting the Mutating Distribution at Antigenic Sites of the Influenza Virus
Overview of our model to calculate the mutating distribution for the HA antigenic sites.
Steps (A–C) illustrate the construction of the nucleotide transition matrix for HA antigens. Steps (D–F) present the mutant simulation and selection for the template sequences. In step (G), the top 100 mutants are re-ranked according to potential dominance likeliness score.
