Figure 2 | Scientific Reports

Figure 2

From: Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3′-sulfo-lactose and 2′-fucosyllactose

Figure 2

Crystal structure of galectin-4N-glycerol complex.

(A) Simulated annealing omit map of galectin-4N binding site with bound glycerol. Galectin-4N binding site residues (green carbons) with bound glycerol (carbon (yellow)) depicted in stick representation. The 2|Fo| − |Fc|αcalc map is illustrated in blue mesh at a 1.0 σ contour level and the |Fo| − |Fc|αcalc map is illustrated in red mesh at a 3.0 σ contour level. The omit map was created by the “composite omit map” task of Phenix89. (B) Binding site interactions of galectin-4N and glycerol. Galectin-4N binding site depicted in green cartoon representation with binding site residues and bound glycerol (carbon (yellow)) represented as sticks. Hydrogen bonds are illustrated as dashed lines.

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