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Figure 1

From: A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics

Figure 1

Synthesis and characterization of ND8008.

(a) Chemical synthesis of ND8008. (b) The NO release rate of ND8008 in vitro was analysed by the Griess assay. 5-isosorbide mononitrate (ISMN) was used as a positive control and dexamethasone (Dex) was used as a negative control. (c) Compound toxicity on murine peritoneal macrophages. For the Control, the same volume of ethanol was added to saline.

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