Figure 3 | Scientific Reports

Figure 3

From: Tunable ultrasensitivity: functional decoupling and biological insights

Figure 3

Causal relationships between molecular regulations (represented by Fmax and r) and sensitivity tuning (changes of Ion and ΔI).

The common parameter values are Wtot = 1, , W0.5 = 0.3, n = 4, r = 1 (when Fmax is varied), Fmax = 0.04 (when r is varied). (A) Targeted regulations (solid arrows) and crosstalks (dashed arrows). (B) Six sets of K and K* values. (C) ΔI as a function of Fmax. Different curves correspond (through color) to different K and K* values. (D) Ion as a function of Fmax. (E) ΔI as a function of r. (F) Ion as a function of r.

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