Figure 5
From: Tunable ultrasensitivity: functional decoupling and biological insights

Effects of the enzyme concentration
on sensitivity.
(A) Five response curves W*(I) that are obtained with five
values and the same other parameters: K = K* = 10−5, Wtot = 1, r = 1, Fmax = 0.04, W0.5 = 0.3, n = 4. (B) Five response curves obtained under the same conditions as (A) except the following two differences. First, K = K* = 10−2. Second, the curves are different in both
and r because we have fixed
. (C) Effects of
on Ion obtained with six sets of K and K* values. The other parameters are the same as in (A). (D) Effects of
on the hysteresis width ΔI.