Figure 3
From: An integrated multi-electrode-optrode array for in vitro optogenetics
Demonstration of biocompatibility and recording capabilities of the MEOA chip.
(a) Confocal fluorescence image of a transduced hippocampal neuronal network (DIV15) cultured on the MEOA. Transduced neurons are shown in red (mCherry), neuronal dendrites in green (Anti-MAP2) and cell nuclei in blue (DAPI). Transduction rate was on average 51.8 ± 13.4% (n = 5 cultures). Brightness and contrast are enhanced for visualization purposes. (b) Representative baseline recording of hippocampal neurons on one electrode contact at DIV13 with an SNR of >10.
