Figure 2
From: Early diagnosis of Alzheimer’s disease from elevated olfactory mucosal miR-206 level
miRNA-206 real-time PCR results for olfactory epithelial samples.
Panel A demonstrates the relative miRNA-206 level (normalized to the U6 level) in each patient. The two cutoff values were determined by receiver operating curve (ROC) analysis, which revealed the highest sum of sensitivity and specificity for the diagnosis of CDR 0.5 or CDR 1 dementia from the entire population. The diagnosis of CDR 0.5 in ROC analysis signifies the detection of patients with a CDR ≥0.5. Panels B and C depict the results of ROC analyses for the diagnosis of CDR 0.5 and CDR 1 dementia, respectively. The areas under the curve (AUCs) are 0.942 and 0.976 for CDR 0.5 and CDR 1 dementia, respectively.
