Figure 1 | Scientific Reports

Figure 1

From: Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier

Figure 1

Choriocarcinoma and HVT cell lines express ABCG2 but not P-gp or MRP1.

(A) Western blot for ABC transporters P-gp, ABCG2 and MRP1 in BeWo, Jeg-3 and HVT cell lysates and positive control HEK cells expressing ABCG2, P-gp, or MRP1. (B) Flow cytometry antibody staining of ABCG2. (C) Flow cytometry antibody staining of Pgp. Data normalized to fluorescence measured in the antibody stained condition for each cell line from three experiments ± SD (*p < 0.05, **p < 0.01 by Student’s t test).

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