Figure 3 | Scientific Reports

Figure 3

From: Knockin of Cre Gene at Ins2 Locus Reveals No Cre Activity in Mouse Hypothalamic Neurons

Figure 3

Efficient and specific Cre-mediated recombination in pancreatic β cells from the islets of Ins2-Cre mice.

Pancreatic cryosections from Ins2-Cre;Rosa-tdTomato mice were subjected to immunostaining for insulin, glucagon, pancreatic polypeptide (PP) and somatostatin. Cre-mediated recombination occurred only in insulin-expressing cells with high efficiency but not in other hormone-expressing islet cells. Scale bar, 50 μm.

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