Table 1 Characteristics of the studies included in the meta-analysis.

From: Role of IL-17A rs2275913 and IL-17F rs763780 polymorphisms in risk of cancer development: an updated meta-analysis

First author

Year

Ethnicity

Tumor type

case

control

Genotyping medthod

Source of control

No. of SNP

cancer risk

Hou

2015

Asian

GC

326

326

MassARRAY

Population

1, 2

No.1 yes

Nemati

2015

Caucasian

CRC

202

203

PCR-RFLP

Hospital

1*, 2

yes

Gao

2015

Asian

GC

572

572

PCR–RFLP

Hospital

1, 2*

No.2 yes

Lv

2015

Asian

CC

264

264

PCR–RFLP

Population

1, 2*

No.1 yes

Lee

2015

Asian

PTC

94

260

TaqMan

Population

1

no risk

Xi

2015

Asian

HCC

155

171

PCR–RFLP

Hospital

1, 2

no risk

Wang

2014

Asian

GC

462

462

PCR–RFLP

Population

1, 2

No.1 yes

Wróbel

2014

Caucasian

AML

62

125

PCR–RFLP

Population

1, 2

No.2 yes

Omrane

2014

Caucasian

CRC

102

139

TaqMan

Population

1

yes

Omrane

2014

Caucasian

CRC

102

139

TaqMan

Population

2

yes

Yin

2014

Asian

EC

380

380

SNPscan

Hospital

1

yes

Li

2014

Asian

HCC

395

174

PCR–RFLP

Hospital

1

yes

Kaabachi

2014

Caucasian

LC

239

258

PCR–RFLP

Population

1, 2

No.2 yes

Zhu

2014

Asian

GC

311

611

MassARRAY

Hospital

1, 2*

No.1 yes

Zhang

2014

Asian

GC

260

512

MassARRAY

Hospital

1*, 2*

yes

Bi

2014

Asian

GC

99

150

PCR-RFLP

Hospital

1, 2

no risk

Rafiei

2013

Caucasian

GC

161

171

PCR–RFLP

Hospital

1

yes

Zhou

2013

Asian

BLC

301

446

TaqMan

Hospital

1, 2

yes

Arisawa

2012

Asian

GC

337

587

PCR-SSCP

Hospital

1

yes

Quan

2012

Asian

CC

311

463

TaqMan

Hospital

1, 2

No.1 yes

Wang

2012

Asian

BC

491

502

SNaPshot

Population

1, 2

No.1 yes

Ruan

2012

Asian

OC

92

38

PCR-RFLP

Hospital

1*, 2*

no risk

Chen

2010

Asian

GC

1042

1090

TaqMan

Population

1

no risk

Wu

2010

Asian

GC

1010

800

PCR–RFLP

Population

1, 2

No.2 yes

Luo

2010

Asian

GC

24

50

PCR-RFLP

Hospital

1*, 2

No.1 yes

Shibata

2009

Asian

GC

287

524

PCR–SSCP

Hospital

1*, 2

No.1 yes

  1. *The P-values of the Hardy-Weinberg equilibrium test of control group less than 0.05.
  2. CRC: colorectal cancer; GC: gastric cancer; CC: cervical cancer; PTC: papillary thyroid cancer; HCC: hepatocellular carcinoma; LC: lung cancer; AML: acute myeloid leukemia; EC: esophageal cancer; BLC: bladder cancer; BC: breast cancer; OC: ovarian cancer; NA: not available; PCR-RFLP: polymerase chain reaction restriction fragment length polymorphism; SSCP: single strand conformation polymorphism; SNP: single-nucleotide polymorphisms; No. of SNP: No.1: rs2275913, No.2: rs763780.