Figure 7 | Scientific Reports

Figure 7

From: MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition

Figure 7

Blocking of miR-101 releases cells from apoptosis and cell cycle arrest.

(A) VHL level changes in MCF-7-miR-101 and MDA-MB-231-miR-101 cells transfected with anti-miR-101 oligos by western blot. (B) Percentage of Annexin V positive cells in MCF-7-miR-101 and MDA-MB-231-miR-101 cells transfected with anti-miR-101 oligos. (C,D) Percentage of G1, S and G2/M phages (C) and G1 phase (D) in MCF-7-miR-101 and MDA-MB-231-miR-101 cells. Data were analyzed using Student’s t-test. *P < 0.05; **P < 0.01; ***P < 0.001.

Back to article page