Figure 1

Cellular response to laser sintered disks with smooth or rough surfaces.
Laser sintered surfaces were polished (A) or treated by blasting with calcium phosphate particles and subsequent acid etching (B) that resulted in combined micro- (top) and nano-roughness (bottom). DNA content (C), osteocalcin (D), osteoprotegerin (E), VEGF (F) and BMP2 (G) production by NHOst cells seeded on disks. Student’s t-test, p < 0.05, *vs. LST-M.