Figure 5

Bone growth into and around endosteal wrap implants on rabbit tibias.
Histological sections of wrap implants stained with Stevenel’s Blue after 1 week ((A), with enlarged (B) showing bone and (C) showing connective tissue), 3 weeks ((D), with enlarged (E,F) showing cartilage and (G) showing woven bone), 6 weeks ((H), with enlarged (I) showing bone in contact with inside of implant and (J) showing new bone around outside of implant) and used to analyze bone-to-implant contact (K). Scale bars for (A–D,H) represent 1 mm, scale bars for (G) and (I) represent 500 um, scale bar for F represents 200 um, scale bar for (J) represents 100 um and scale bar for (E) represents 20 um. For histomorphometric analysis, one-way ANOVA was performed with Bonferroni’s correction, p < 0.05, *vs. 1 week, # vs. 3 weeks.