Figure 4

Phenformin and thiamine partially inhibit DNR uptake in TOV2223G cells.
Cells were seeded in 96-well plates and DNR uptake was monitored as in Fig. 1C, but when added together with either choline (CHL), ergothioneine (ERGO), phenoformin (PHEN), thiamine (THIA), spermidine (SPD) or L-carnitine (L-car). Cells without DNR were designated as the control (Ctrl). Results are expressed as the mean ± S.D. from three separate experiments.