Figure 5

The difference in DREEM signals from DNA bound by TRF2 complexes (DNA bound) and DNA alone.
(a,b) Contour maps of DREEM phase images showing lower (a) and higher (b) DREEM phase signals for DNA bound by TRF2 compared to DNA alone. The image in (b) is the contour map of the TRF2-DNA complex in Fig. 4b (third row). (c) the DREEM phase signal difference (DNA bound by TRF2 – DNA alone, N = 60) for individual large TRF2-DNA complexes. Each bar represents the difference between DREEM phase signals from DNA bound by individual large TRF2 complexes and DNA alone in the same images. The error bars represent standard deviations of the measurement. Labels (a,b) indicate the data sets measured from DREEM images of complexes shown in panels (a,b), respectively.