Figure 4

The ASC-dependent inflammasome does not influence deposition of albumin and fibrinogen.
PMMA bead aggregates from ASC−/−, NLRP3−/− or AIM2−/− mice were sectioned at 5 μm for immunohistochemistry staining of (a) albumin and (b) fibrinogen as observed by brown staining. Wild-type mice are shown for comparison. Scale bar, 250 μm. Representative images are shown of the 4–8 mice per group per time point.