Table 2 Association of depression with RA stratified by sex, age, and follow-up years.

From: Bidirectional associations between rheumatoid arthritis and depression: a nationwide longitudinal study

Variables

Non-RA cohort

RA cohort

HR (95% CI)

Case

PYs

Incidence

Case

PYs

Incidence

Crude

Adjusted

All

1075

120100.95

8.95

958

61075.48

15.69

1.75 (1.60–1.91)

1.69 * (1.51–1.87)

Sex

 Female

834

79153.66

10.54

749

40500.41

18.49

1.76 (1.57–1.93)

1.73 ξ (1.50–1.84)

 <=40

123

14034.12

8.76

130

6855.65

18.96

2.16 (1.67–2.73)

2.14 Υ (1.62–2.69)

 41–60

427

38820.73

10.99

365

19759.52

18.47

1.68 (1.45–1.99)

1.60 Υ (1.35–1.90)

 >60

284

26298.81

10.79

254

13885.25

18.29

1.67 (1.42–1.92)

1.58 Υ (1.37–1.82)

 Male

241

40947.29

5.89

209

20575.07

10.16

1.72 (1.43–2.06)

1.65 ξ (1.33–1.94)

 <=40

28

7405.85

3.78

40

3548.01

11.27

2.97 (1.81–4.77)

2.76 Υ (1.83–4.59)

 41–60

90

17265.70

5.21

78

8682.50

8.98

1.72 (1.27–2.33)

1.59 Υ (1.17–2.17)

 >60

123

16275.75

7.56

91

8344.56

10.90

1.44 (1.10–1.88)

1.33 Υ (1.01–1.75)

Follow–up (years)

 ≦ 2

161

2481.50

64.88

195

1328.31

146.77

2.25 (1.71–2.44)

1.98 * (1.43–2.15)

 3–5

483

8666.64

55.73

443

5423.28

81.68

1.48 (1.34–1.73)

1.47 * (1.28–1.76)

 >5

431

108952.81

3.96

320

54323.89

5.89

1.50 (1.30–1.74)

1.48 * (1.25–1.69)

  1. Incidence rate is per 1,000 PYs.
  2. ΥModel adjusted for urbanization level, monthly income, and comorbidity.
  3. ξModel adjusted for age, urbanization level, monthly income, and comorbidity.
  4. *Model adjusted for age, gender, urbanization level, monthly income, and comorbidity.