Figure 8
Enrichment analysis of genes in windows with triple top-5% levels of SNPdb, SNP1K and CNVG features.
The 802 genes in the 54 hotspot 500-kb windows are functionally annotated using DAVID Bioinformatics Resources based on (a) GOTERM, (b) KEGG, (c) INTERPRO databases. Only those gene-groups yielding <0.05 Bonferroni corrected p-value, Benjamini corrected p-value as well as FDR q-value are considered to be significantly gene-enriched. The bars in each of (a–c) show the number of genes enriched in various gene groups and the different bars are arranged from top down in order of increasing Bonferroni corrected p-values.
