Figure 2: Induced expression of M. sexta Dorsal and Rel2 in hemocytes.

Total RNA samples were prepared from hemocytes of naïve larvae or larvae injected with E. coli, S. aureus and S. cerevisiae (A–C), and real-time PCR was performed for MsDorsal, MsRel2 and MsRel2B as described in Fig. 1. Cytoplasmic (Cp) and nuclear (Nu) proteins were also extracted from hemocytes of naïve and E. coli-injected larvae, and proteins were separated on 12% SDS-PAGE. MsDorsal in the protein extracts was detected by Western blot analysis using rabbit polyclonal antibody to recombinant MsDorsal-RHD (D). Arrow indicates MsDorsal, while arrow head indicates a possible MsDorsal dimer or non-specific protein band recognized by anti-MsDorsal antibody.