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Figure 2

From: Diet-induced changes in maternal gut microbiota and metabolomic profiles influence programming of offspring obesity risk in rats

Figure 2

Effect of maternal oligofructose supplementation on offspring body weight and body composition.

Pregnant and lactating diet-induced obese dams were fed either a high-fat/sucrose diet (HFS obese control group), the high-fat/sucrose diet supplemented with 10% wt/wt oligofructose (OFS group), or a restricted amount of the high-fat/sucrose diet in order to match body weight to the OFS dams (WM). Offspring body weight was measured weekly and body composition analyzed at weaning using DXA scan. Offspring body weight was calculated using litter averages as individual values. (a) Offspring body weight throughout lactation (HFS, n = 12; OFS, n = 12; WM, n = 9). (b) Offspring fat mass and percent body fat (HFS offspring, n = 31, 15 males and 16 females; OFS offspring, n = 29, 13 males and 16 females; WM offspring, n = 30, 13 males and 16 females). Values are mean ± SEM. Mean values without a common letter are significantly different using one-Way ANOVA (P < 0.05).

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