Figure 2: Expression promiscuity and agreement with tissue of pathology of cancer genes. | Scientific Reports

Figure 2: Expression promiscuity and agreement with tissue of pathology of cancer genes.

From: Cell type-specific properties and environment shape tissue specificity of cancer genes

Figure 2

(A) The number of tissues in which a cancer gene is expressed is shown versus its specificity. The small correlation between these variables (0.12; Pearson correlation) is not significant (p > 0.05). (B) We determined the tissue with the highest expression level of 130 highly specific-cancer genes (i.e., only associated with one type of cancer) and found that only 4 are expressed highest in the tissue (or in a closely related tissue) from which the respective cancer originates.

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