Figure 3: Suppression of gene expression in the presence of varying concentrations of free ASODN or MNP-conjugated ASODN.
From: A molecular nanodevice for targeted degradation of mRNA during protein synthesis
Suppression rate was determined by the ratio of the sfGFP fluorescence in the presence and absence of ASODS. (a) Free ASODN. (b) MNP conjugated with 5′-end of ASODN. (c) MNP conjugated with 3′-end of ASODN. Error bars in the graph indicate standard deviations from three independent reaction samples. *p-value < 0.05. **p-value < 0.01. NS, not significant.
