Figure 5 | Scientific Reports

Figure 5

From: Learning (from) the errors of a systems biology model

Figure 5

Detecting the target nodes of simulated model errors in the UV-B signalling network.

(a) All nodes and all pairs of nodes were perturbed by a simulated model error. Nodes and are omitted, since the simulated error signal had no effect on the output. The rows and the columns correspond to the true target nodes of the model error and the numbers in the cells are the nodes found by the dynamic elastic-net (NA means that no second node was assigned). Gray cells indicate errors made by the dynamic elastic-net for unobservable model errors. (b) An example for an unobservable model error. The true target nodes of the model error are , but the dynamic elastic-net predicts the target nodes . (c) Refitting the dynamic elastic-net under the constraint provides an alternative solution. The other two combinations and of the nodes did not fit the output data.

Back to article page