Figure 7 | Scientific Reports

Figure 7

From: Regulating ehrlich and demethiolation pathways for alcohols production by the expression of ubiquitin-protein ligase gene HUWE1

Figure 7

The overview of HUWE1 mediating the regulation of ehrlich and demethiolation pathways.

Overexpression of HUWE1 increased the expression of ehrlich pathway genes ARO8-2 (ARO9 in S. cerevisiae), BAT (BAT1 in S. cerevisiae) and demethiolation pathway gene STR3, but suppressed the expression of ehrlich pathway gene PDC (PDC1, PDC5, PDC6, ARO10 in S. cerevisiae). The corresponding metabolic products changed accordingly. This indicated that HUWE1 regulated the ehrlich and demethiolation pathways in eukaryotic cell.

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