Table 2 Change of Clinical Characteristics after Treatment.

From: Time course and factors predicting arterial stiffness reversal in patients with aldosterone-producing adenoma after adrenalectomy: prospective study of 102 patients

 

Baseline

6 month

12 month

P value(baseline-6 months)

P value(6–12 months)

P value(baseline-12 months)

SBP (mmHg)

157 ± 23

143 ± 20

141 ± 22

<0.001

0.173

<0.001

DBP (mmHg)

92 ± 14

88 ± 12

86 ± 11

0.004

0.106

<0.001

baPWV (cm/s)

1636 ± 310

1533 ± 278

1562 ± 313

<0.001

0.248

0.006

haPWV (cm/s)

1096 ± 138

1048 ± 129

1049 ± 130

<0.001

0.415

0.005

Potassium (mmol/L)

3.5 ± 0.8

4.4 ± 0.5

4.4 ± 0.4

<0.001

0.545

<0.001

PAC (ng/dL)

61 ± 40

28 ± 19

33 ± 25

<0.001

0.018

<0.001

PRA (ng/mL/hr)

1.0 ± 3.1

3.1 ± 6.4

4.5 ± 10.8

<0.001

0.216

<0.001

Log PAC

1.7 ± 0.3

1.4 ± 0.3

1.5 ± 0.2

<0.001

0.009

<0.001

Log PRA

−0.8 ± 0.8

0.1 ± 0.6

0.2 ± 0.6

<0.001

0.110

<0.001

Log ARR

2.3 ± 0.9

1.3 ± 0.6

1.3 ± 0.6

<0.001

0.712

<0.001

  1. Values are mean ± SD. SBP = systolic blood pressure; DBP = diastolic blood pressure; PAC = plasma aldosterone concentration; PRA = plasma renin activity; Log PAC = log-transformed plasma aldosterone concentration; Log PRA = log-transformed plasma renin activity; Log ARR = log-transformed aldosterone to renin ratio; baPWV = brachial-ankle pulse wave velocity; haPWV: = heart-ankle pulse wave velocity.