Table 3 PfTET3 activity at different metal-temperature using 5 mM Lys-pNa.

From: Tuned by metals: the TET peptidase activity is controlled by 3 metal binding sites

Metal

% Relative activity T = 20 °C

% Relative activity T = 50 °C

% Relative activity T = 85 °C

none

100

100

100

Zn2+ 0.1mM

55.5

61.6

52.3

Co2+ 0.1mM

50.3

67.0

229.4

Mn2+ 0.1mM

82.8

75.1

38.0

Zn2+ 1mM

13.5

15.5

35.4

Co2+ 1mM

14.3

35.6

107.2

Mn2+ 1mM

47.5

27.2

15.9