Figure 1: Key features of mod genes and alleles. | Scientific Reports

Figure 1: Key features of mod genes and alleles.

From: Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulence

Figure 1

(a) Schematic diagram of mod genes (represented by an arrow), showing the location of the phase variable DNA repeats, the DPPY and FxGxG motifs, and the central DNA recognition domain (DRD). For (b) modA, (c) modB and (d) modD genes, the location and type of phase variable repeats are shown, along with the location of the DRD and a graphical representation of a clustalW alignment of reference alleles [generated in JalView, with identical residues shown as vertical blue lines]. Strains that define the mod alleles are shown on the right (Hi: Haemophilus influenzae; Nm: N. meningitidis; Nl: N. lactamica; Np: N. polysaccharea; Nc: N. cinerea; Nmu: N. mucosa). For modA (b), the location of the 15-nucleotide deletion is also shown.

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