Table 1 Clinical characteristics of 354 high-grade gliomas by IHC.

From: Low c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas

Characteristics

Grade III N = 179

Grade IV N = 175

Gender

ā€ƒFemale/male

79/99 (44%)

67/108 (38%)

Age

ā€ƒMedian (range)

42 (14–74)

51 (9–81)

KPS score

ā€ƒMedian (range)

80 (50–98)

80 (50–70)

Median OS

ā€ƒ(days, 95% Cl)

704 (1.4–3.2)

382 (1.0–2.2)

Median PFS

ā€ƒ(days, 95% Cl)

510 (1.6–3.6)

255 (1.0–2.1)

Extent of resection

ā€ƒGTR (%)

43%

48%

  1. Abbreviations: IHC, mmunohistochemistry; KPS, Karnofsky Performance Status; OS, overall survival; PFS, progression-free survival; GTR, gross total resection.