Figure 4
From: Multi-functionalized carbon dots as theranostic nanoagent for gene delivery in lung cancer therapy
Diagnostic property of fc-rPEI-Cdots nanoparticles.
(A) Absorption and photoluminescence spectrum of rPEI-Cdots, PEI-Cdots, folate and fc-rPEI-Cdots. Insert: Photoluminescence (PL) of rPEI-Cdots and fc- rPEI-Cdots under UV excitation. Strongest photoluminescence of fc-rPEI-Cdots appeared at 460 nm when excited by 360 nm. (B) The PL intensity of rPEI-Cdots and fc-rPEI-Cdots in different pH environment (pH 5, 8). (C) Enhanced accumulation of fc-rPEI-Cdots in H460 could be observed by fluorescent microscopy. (D) fc-rPEI-Cdots (blue) and FAM labeled-siRNA (green) were delivered intracellularly.
